412935-69-4Relevant academic research and scientific papers
Influence of various central moieties on the hypolipidemic properties of long hydrocarbon chain diols and diacids
Oniciu, Daniela C.,Dasseux, Jean-Louis H.,Yang, Jing,Mueller, Ralf,Pop, Emil,Denysenko, Anna,Duan, Caiming,Huang, Tian-Bao,Zhang, Lianhao,Krause, Brian R.,Drake, Sandra L.,Lalwani, Narendra,Cramer, Clay T.,Goetz, Brian,Pape, Michael E.,McKee, Andrew,Fici, Gregory J.,Lutostanski, Janell M.,Brown, Stephen C.,Bisgaier, Charles L.
, p. 334 - 348 (2007/10/03)
A series of long (11-15) hydrocarbon chain diols and diacids with various central functional groups and terminal gem-dimethyl or -methyl/aryl substituents was synthesized and evaluated in both in vivo and in vitro assays for its potential to favorably alt
Sulfide and disulfide compounds and compositions for cholesterol management and related uses
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, (2008/06/13)
The invention encompasses novel sulfide and disulfide compounds, compositions comprising sulfide and disulfide compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disord
SULFIDE AND DISULFIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES
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Page/Page column 216, (2010/02/13)
The invention encompasses novel sulfide and disulfide compounds, compositions comprising sulfide and disulfide compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising an ether compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing Alzheimer's Disease, Syndrome X, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, renal disease, cancer, inflammation, and impotence. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.
Sulfide and disulfide compounds and compositions for cholesterol management and related uses
-
, (2008/06/13)
The present invention relates to novel sulfide and disulfide compounds, compositions comprising sulfide and disulfide compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism
