412949-79-2

Upstream product

• 412949-76-9 ethyl 4-methoxy-2,6-dimethylbenzoate 
• 100667-93-4 ethyl 2,6-dimethyl-4-methoxycyclohexa-1,3-dienecarboxylate 
• 412949-78-1 ethyl 2-ethoxycarbonylmethyl-4-methoxy-6-methylbenzoate 

Relevant academic research and scientific papers

Synthesis and cytotoxic activity of tetracenomycin d and of saintopin analogues

Regiospecific synthesis of title compounds is based either on cycloaddition of ketene acetals derived from Hagemann's ester or of homophthalic anhydrides. Thus, tetracenomycin D and 3,8-di-O-methyl saintopin have been prepared in few steps. New derivatives of 10-deoxysaintorpin have been also obtained. Evaluation of their cytotoxicity against L1210 leukemia cells are reported. Copyright