41295-62-9Relevant articles and documents
A naphtho[2,1-b]furan as a new fluorescent label: Synthesis and spectral characterisation
Piloto, Ana M.,Costa, Susana P. G.,Gon?alves, M. Sameiro T.
, p. 4757 - 4760 (2005)
A fluorescent naphthofuran was synthesised from an oxobenzopyran by alkaline ring contraction and coupled with various l-amino acids at their N-terminus or at side-chain functional groups, in order to evaluate its applicability as a fluorescent label for
Synthesis of novel coumarin and benzocoumarin derivatives and their biological and photophysical studies
Abd-El-Aziz, Alaa S.,Mohamed, Hany M.,Mohammed, Shawkat,Zahid, Shamsulhaq,Ata, Athar,Bedair, Ahmed H.,El-Agrody, Ahmed M.,Harvey, Pierre D.
, p. 1287 - 1301 (2008/09/18)
(Chemical Equation Presented) Several derivatives of coumarin-3N- carboxamides (3-21) have been prepared via the reaction of the coumarin-3-carbonyl chloride (1) with a number of nucleophiles. Novel double-headed coumarin-3N-carboxamides (26-33) were also produced using the same method. The Pechmann-Duisberg reaction was applied to prepare new benzo[f]- benzo[h]coumarins and 4-(chloromethyl)-pyrano[3,2-c]coumarin-2-one (36-42). The reaction of 1-chloromethylbenzo[f]coumarins (36) with cyanide anion under different reaction conditions was also investigated in order to assess its suitability for nucleophilic substitution reactions as well as ring transformation products (43-49). Synthesis of 1-((benzo[d]thiazol-2-yl)methyl)- 9-hydroxybenzo[f]coumarin (50) represented the first example of methylene bridge-head heterocycle-containing benzo[f]coumarin. Some of the newly prepared coumarins exhibited anti-bacterial activity against Gram Positive and Gram negative bacteria. Compound 36d was found to be active against all the screened bacteria. Photophysical studies were performed on selected fluorescent benzo[f]- and benzo[h]coumarin and the quantum yields were also calculated. All new compounds were characterized by IR, MS, 1H and 13C NMR, as well as elemental analysis.
Synthesis of 2-nitronaphtho [2,1-b] furan carboxylic acids derivatives
Einhorn,Lamotte,Buisson,et al.
, p. 143 - 147 (2007/10/02)
2-Nitro naphthofurans carrying a carboxyl group, an acetyl or oxy acetyl chain outer homocycle are obtained - either directly or through their ester - by condensations of bromonitromethane with suitably substituted ortho hydroxy naphthoic aldehydes. 2-Nitro naphthofuran, which bears an acetyl chain on the second carbon of its heterocycle, is formed by direct nitration of the acid or of a (naphtho[2,1-b]-3-furyl)-ecetic ester. These acids and their corresponding esters are nearly always less active against bacteria and protozoa than the reference 2-nitro naphthofurans.
