41318-76-7

Upstream product

• 123-31-9 hydroquinone 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 3061-36-7 1,4-diphenoxybenzene 

Downstream Products

• 72659-54-2 1,4-Bis(p-diphenylphosphinophenoxy)benzene 
• 2455-43-8 bis(phenoxyphenyl) ether of p-hydroxyquinone 

Relevant academic research and scientific papers

Selective displacement of aryl fluorides with hydroquinone: Synthesis of 4-phenoxyphenols

The selective displacement of a variety of aryl fluorides with hydroquinone has been achieved to give substituted 4-phenoxyphenols 3. In some cases the addition of 18-crown-6 resulted in a significant rate enhancement, and the reactions could be carried out at lower temperature. One of these derivatives, 3a (X = Cl) was converted to 2-propyl-4-(4-chlorophenoxy)phenol 2a, a precursor to the PPARγ receptor agonist 1.