4133-05-5Relevant articles and documents
Synthesis of bis-dibenzonaphthyridines and evaluation of their antibacterial activity
Sangeetha,Manoj,Jayabalan,Venkateswaran
, p. 845 - 855 (2015/10/28)
Reaction of phthalic acid with 2-methyl-4-N-phenylaminoquinoline under PPA condition resulted in the formation of 6-methyldibenzo[b, h][1,6]naphthyridines, whereas the same reaction with 2,4-bis(N-phenylamino)quinoline resulted in the dimeric dibenzo[b, h][1,6]naphthyridines. A novel mechanism has been proposed to explain the formation of the unexpected product. Screening for the antibacterial activity against various pathogens, proved that the dimeric analogs showed a better antibacterial activity when compared to their monomeric analogs.