41339-64-4

Basic information

• Product Name: 2-(5-nitro-1H-indol-3-yl)ethanol
• Synonyms: 1H-Indole-3-ethanol, 5-nitro-; 5-Nitro-1H-indole-3-ethanol
• CAS NO: 41339-64-4
• Molecular Formula: C₁₀H₁₀N₂O₃
• Molecular Weight: 206.198
• Mol File: 41339-64-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 451.891°C at 760 mmHg
• Flash Point: 227.096°C
• Density: 1.432g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.708
• CAS DataBase Reference: 2-(5-nitro-1H-indol-3-yl)ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(5-nitro-1H-indol-3-yl)ethanol(41339-64-4)
• EPA Substance Registry System: 2-(5-nitro-1H-indol-3-yl)ethanol(41339-64-4)

Safety Data

• Hazardous Substances Data: 41339-64-4(Hazardous Substances Data)

Upstream product

• 166171-96-6 3-[2-(tert-butyldimethylsilyloxy)ethyl]-5-nitro-2-(trimethylsilyl)-1H-indole 
• 6970-51-0 ethyl (5-nitro-1-H-3-indolyl)acetate 

Downstream Products

• 1004541-46-1 (+/-)-2-(2-(4-(Dimethylamino)-4-phenylcyclohex-1-enyl)-5-nitro-1H-indol-3-yl)ethanol 

Relevant articles and documents

E-SELECTIN ANTAGONISTS

Compounds, compositions and methods are provided for inhibiting in vitro and in vivo processes mediated by E-selectin binding. More specifically, particular glycomimetic compounds are described, wherein the compounds are E- selectin antagonists.

First heterogeneous ligand- and salt-free larock indole Synthesis

A new ligand- and salt-free procedure using heterogeneous palladium catalysts for the Larock indole and benzofuran synthesis is reported. After optimisation of the reaction conditions, good to high isolated yields have been achieved for a variety of structures. Recycling studies have shown that the palladium catalysts can be readily recovered and reused. Reactions and recovery of the palladium catalysts can be carried out in the presence of air, without any particular precaution.

Indolylalkylpiperidines

1-(Indolyl-3-alkyl)-3 or 4-(ureido or guanidino)-piperidines, e.g. those of the formula STR1 R= H; alkyl; free, etherified or esterified OH or SH; CF3, NO2 or NH2 m= 1-4; n= 2 or 3; X= O, S or NH acyl derivatives and salts thereof are antihypertensive agents.