413603-69-7

Basic information

• Product Name: [1-(4-oxo-2-phenyl-butyl)-1H-imidazol-4-yl]-acetonitrile
• CAS NO: 413603-69-7
• Molecular Weight: 253.304
• Mol File: 413603-69-7.mol

Chemical Properties

• CAS DataBase Reference: [1-(4-oxo-2-phenyl-butyl)-1H-imidazol-4-yl]-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(4-oxo-2-phenyl-butyl)-1H-imidazol-4-yl]-acetonitrile(413603-69-7)
• EPA Substance Registry System: [1-(4-oxo-2-phenyl-butyl)-1H-imidazol-4-yl]-acetonitrile(413603-69-7)

Safety Data

• Hazardous Substances Data: 413603-69-7(Hazardous Substances Data)

Upstream product

• 130284-35-4 2-phenyl-pent-4-en-1-ol 
• 1575-70-8 2-phenyl-pent-4-enoic acid 
• 413603-62-0 [1-(2-phenyl-pent-4-enyl)-1H-imidazol-4-yl]-acetonitrile 
• 103-82-2 phenylacetic acid 

Relevant articles and documents

Design, synthesis, and SAR of heterocycle-containing antagonists of the human CCR5 receptor for the treatment of HIV-1 infection

Replacement of the large hydantoin-indole moiety from our previous work with a variety of smaller heterocyclic analogues gave rise to potent CCR5 antagonists having binding affinity comparable to the hydantoin analogues. The synthesis, SAR, and biological profiles of this class of antagonists are described.