413611-08-2

Upstream product

• 100-46-9 benzylamine 
• 210704-33-9 5-(1-hydroxyethylidene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione 

Downstream Products

• 571178-29-5 5-(1-hydrazinoethylidene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione 
• 571178-30-8 5-[1-(3-{benzyl-[4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-amino}-propylamino)-ethylidene]-1,3-dimethyl-pyrimidine-2,4,6-trione 
• 571178-26-2 5-[1-(3-benzylaminopropylamino)ethylidene]-1,3-dimethylhexahydro-2,4,6-pyrimidinetrione 

Relevant academic research and scientific papers

Reaction of 1,3-dimethyl-5-acetyl-barbituric acid (DAB) with primary amines. Access to intermediates for selectively protected spermidines

The ability of 1,3-dimethyl-5-acetyl-barbituric acid (DAB) to react with primary amines in a chemoselective fashion was applied to the synthesis of a selectively protected spermidine.