413611-14-0Relevant academic research and scientific papers
Synthesis of highly functionalized barbituric acids and study of their interactions with p-glycoprotein and Mg2+ - Potential candidates for multi drug resistance modulation
Singh, Palwinder,Kaur, Jatinder,Bhardwaj, Atul
experimental part, p. 1256 - 1262 (2010/05/02)
A number of barbituric acids with appropriate substituent at C-5 position were synthesized and investigated for their interactions with p-gp and Mg2+. Compounds 5, 6, 8-10, 12-14 and 16 increased the basal activity of p-gp by more than 50% at 0
