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41372-08-1

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41372-08-1 Usage

Chemical Properties

White Solid

Uses

Different sources of media describe the Uses of 41372-08-1 differently. You can refer to the following data:
1. Potent inhibitor of invertase and glucosidase inhibitor with a different specificity of action to DNJ and castanospermine. Inhibits glucosidase I.
2. Antihypertensive agent.

Biological Activity

l-(-)-α-methyldopa (hydrate) is an alpha-adrenergic agonist (selective for α2-adrenergic receptors) psychoactive drug used as a sympatholytic or antihypertensive.

Purification Methods

Recrystallise methyldopa from H2O. [Reinhold et al. J Org Chem 33 1209 1968.] The L-isomer forms a sesquihydrate from H2O m 302-304o (dec), and the anhydrous crystals are hygroscopic,[] 23D -4.0o (c 1, 0.1N HCl), []546 +154.5o (c 5, CuSO4 solution). It has max at 281nm ( 2780). Its solubility in H2O at 25o is ~10mg/mL and the pH of an aqueous solution is ~5.0. It is insoluble in most organic solvents. [Stein et al. J Am Chem Soc 77 700 1955, Beilstein 4 IV 2505.]

Check Digit Verification of cas no

The CAS Registry Mumber 41372-08-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,3,7 and 2 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 41372-08:
(7*4)+(6*1)+(5*3)+(4*7)+(3*2)+(2*0)+(1*8)=91
91 % 10 = 1
So 41372-08-1 is a valid CAS Registry Number.
InChI:InChI=1/2C10H13NO4.3H2O/c2*1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6;;;/h2*2-4,12-13H,5,11H2,1H3,(H,14,15);3*1H2/t2*10-;;;/m00.../s1

41372-08-1 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (H56704)  (-)-3,4-Dihydroxy-alpha-methyl-L-phenylalanine sesquihydrate, 99%   

  • 41372-08-1

  • 1g

  • 124.0CNY

  • Detail
  • Alfa Aesar

  • (H56704)  (-)-3,4-Dihydroxy-alpha-methyl-L-phenylalanine sesquihydrate, 99%   

  • 41372-08-1

  • 5g

  • 435.0CNY

  • Detail
  • Sigma-Aldrich

  • (Y0001083)  Methyldopa for system suitability  European Pharmacopoeia (EP) Reference Standard

  • 41372-08-1

  • Y0001083

  • 1,880.19CNY

  • Detail
  • USP

  • (1426002)  Methyldopa  United States Pharmacopeia (USP) Reference Standard

  • 41372-08-1

  • 1426002-500MG

  • 4,662.45CNY

  • Detail
  • Aldrich

  • (857416)  (−)-3-(3,4-Dihydroxyphenyl)-2-methyl-L-alaninesesquihydrate  99%

  • 41372-08-1

  • 857416-5G

  • 596.70CNY

  • Detail

41372-08-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name L-α-Methyl DOPA Hydrate

1.2 Other means of identification

Product number -
Other names α-Methyldopa sesquihydrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:41372-08-1 SDS

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