41424-36-6 Usage
Description
1,3,5-Tribromo-2-methoxy-4-methylbenzene, with the CAS number 41424-36-6, is an organic compound that is primarily utilized in the field of organic synthesis. It is a brominated aromatic compound characterized by the presence of three bromine atoms at the 1, 3, and 5 positions, a methoxy group at the 2 position, and a methyl group at the 4 position on a benzene ring.
Uses
Used in Organic Synthesis:
1,3,5-Tribromo-2-methoxy-4-methylbenzene is used as a key intermediate in the synthesis of various organic compounds. Its unique structure, featuring bromine atoms and functional groups, allows it to participate in a range of chemical reactions, such as substitution, addition, and coupling reactions, leading to the formation of diverse organic molecules with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,3,5-tribromo-2-methoxy-4-methylbenzene is used as a building block for the development of new drugs. Its structural features make it a valuable component in the design and synthesis of novel therapeutic agents, particularly those targeting specific biological receptors or enzymes.
Used in Chemical Research:
1,3,5-Tribromo-2-methoxy-4-methylbenzene is also employed in chemical research as a model compound for studying various reaction mechanisms and exploring the reactivity of different functional groups. This helps researchers gain a deeper understanding of the underlying principles governing chemical reactions and aids in the development of new synthetic strategies and methodologies.
Used in Material Science:
In the field of material science, 1,3,5-tribromo-2-methoxy-4-methylbenzene can be used as a component in the development of new materials with specific properties, such as improved thermal stability, flame retardancy, or chemical resistance. Its bromine-containing structure can contribute to the enhancement of these properties in the resulting materials.
Check Digit Verification of cas no
The CAS Registry Mumber 41424-36-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,4,2 and 4 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 41424-36:
(7*4)+(6*1)+(5*4)+(4*2)+(3*4)+(2*3)+(1*6)=86
86 % 10 = 6
So 41424-36-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H7Br3O/c1-4-5(9)3-6(10)8(12-2)7(4)11/h3H,1-2H3
41424-36-6Relevant articles and documents
Effect of cyclodextrins on electrophilic aromatic bromination in aqueous solution
Dumanski, Paul G.,Easton, Christopher J.,Lincoln, Stephen F.,Simpson, Jamie S.
, p. 1107 - 1111 (2007/10/03)
Cyclodextrins act as molecular reactors to change the ratios of the products of reactions of anisole, acetanilide, 3-methylanisole, and 3-methylacetanilide with pyridinium dichlorobromate. With anisole and acetanilide, bromination at the para position is favoured over ortho substitution, and the effect is greatest with α-cyclodextrin. In the reactions of the methylanisole and methylacetanilide, the cyclodextrins afford higher yields of monobrominated products and less of the di- and tribromides, and β-cyclodextrin has the greatest effect. These outcomes can be attributed to inclusion of the substrates within the cyclodextrins restricting access of the reagent adjacent to the methoxy and acetamido groups. The yields of 4-bromoanisole, 4-bromoacetanilide, 4-bromo-3-methylanisole, and 4-bromo-3-methylacetanilide are thus increased from 73 to 94, 55 to 98, 37 to 86, and 39 to 72%, respectively. Perhaps more significantly, the quantities of the corresponding by-products are substantially reduced, from 27 to 6, 45 to 2, 63 to 14, and 61 to 28%. Since the reactions occur readily in water at ambient temperature, the cyclodextrins make them very efficient.
