4145-98-6Relevant academic research and scientific papers
Gene delivery mediated by liposome-DNA complex with cleavable PEG surface modification
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, (2008/06/13)
A liposome composition and method for delivery of a nucleic acid in vivo or ex vivo is described. The liposomes in the composition are comprised of (i) a cationic lipid and (ii) a lipid joined to a hydrophilic polymer by a releasable linkage. The liposomes are associated with a nucleic acid for delivery to a cell.
Liposome composition for delivery of nucleic acid
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, (2008/06/13)
A liposome composition for delivery of a nucleic acid in vivo or ex vivo is described. The liposomes in the composition are comprised of (i) a lipid that is neutral in charge at physiologic pH and positively charged at pH values less than physiologic pH and (ii) a lipid joined to a hydrophilic polymer by a dithiobenzyl linkage. The liposomes are associated with a nucleic acid for delievery to a cell.
Releasable linkage and compositions containing same
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, (2008/06/13)
A compound comprised of a hydrophilic polymer covalently yet reversibly linked to a amine-containing ligand through a dithiobenzyl linkage is described.
Process for producing cysteamines and/or cystamines
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, (2008/06/13)
Specific cysteamines and/or cystamines are produced by a process which comprises causing (A) an aminoalkyl sulfate ester and (B) hydrogen sulfide and an alkali polysulfide formed from an alkali hydrogen sulfide and sulfur to react.
