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2,3-dihydro-1,3,3-trimethyl-2-methylene-1H-pyrrolo[2,3-b]pyridine, commonly known as Harman, is a naturally occurring alkaloid compound belonging to the beta-carboline family. It is found in various plant sources, particularly the Peganum harmala plant, and is known for its psychoactive properties. Harman has been studied for its potential neuroprotective and antioxidant properties, as well as its possible role in the treatment of neurological disorders and as an anti-cancer agent. However, its psychoactive effects and potential toxicity necessitate further research into its pharmacological properties and therapeutic applications.

41450-85-5

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41450-85-5 Usage

Uses

Used in Neuroprotective Applications:
Harman is used as a neuroprotective agent for its potential to protect neurons from damage and degeneration, which may be beneficial in the treatment of neurological disorders.
Used in Antioxidant Applications:
As an antioxidant, Harman is utilized to neutralize harmful free radicals and reduce oxidative stress, which can contribute to various diseases and aging processes.
Used in Cancer Treatment Research:
Harman is investigated as a potential anti-cancer agent, with studies exploring its ability to inhibit cancer cell growth and induce apoptosis in certain types of cancer.
Used in Understanding Hallucinogenic Mechanisms:
Due to its psychoactive properties, Harman serves as a tool for researchers to study the mechanisms of hallucinogenic drugs, potentially leading to advancements in the development of novel therapeutic agents for mental health disorders.
Used in Traditional Medicine and Shamanic Practices:
Harman has been employed in traditional medicine and shamanic practices for its psychoactive effects, although its use in these contexts requires careful consideration due to potential toxicity and side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 41450-85-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,4,5 and 0 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 41450-85:
(7*4)+(6*1)+(5*4)+(4*5)+(3*0)+(2*8)+(1*5)=95
95 % 10 = 5
So 41450-85-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N2/c1-8-11(2,3)9-6-5-7-12-10(9)13(8)4/h5-7H,1H2,2-4H3

41450-85-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3,3-trimethyl-2-methylidenepyrrolo[2,3-b]pyridine

1.2 Other means of identification

Product number -
Other names 1,3,3-trimethyl-2-methylene-7-azaindole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:41450-85-5 SDS

41450-85-5Relevant academic research and scientific papers

Red colouring photochromic 6′-substituted spiroindolinonaphth[2,1-b][1,4]oxazines

Rickwood,Marsden,Ormsby,Staunton,Wood,Hepworth,Gabbutt

, p. 17 - 24 (2007/10/02)

Electron donating/withdrawing substituents and electronegative centres have been successfully employed in substantially widening the range of photo-generated colours available in the spiroindolinonaphthoxazine class of photochromic materials.

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