41498-07-1

Basic information

• Product Name: 4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE
• Synonyms: 4-BROMO-5-NITRO-2-THIOPHENECARBOXALDEHYDE;4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE;4-BroMo-5-nitrothiophene-2-carbaldehyde
• CAS NO: 41498-07-1
• Molecular Formula: C₅H₂BrNO₃S
• Molecular Weight: 236.045
• EINECS: 200-589-5
• Product Categories: Thiophenes
• Mol File: 41498-07-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 301.573 °C at 760 mmHg
• Flash Point: 136.187 °C
• Appearance: /
• Density: 1.99 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.696
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE(41498-07-1)
• EPA Substance Registry System: 4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE(41498-07-1)

Safety Data

• Hazardous Substances Data: 41498-07-1(Hazardous Substances Data)

Usage

General Description

4-Bromo-5-nitrothiophene-2-carboxaldehyde is a chemical compound with the molecular formula C6H3BrNO3S. It is a yellow solid that is used in chemical synthesis and drug development. 4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE contains a bromine atom, a nitro group, and a thiophene ring, which gives it unique chemical properties. 4-Bromo-5-nitrothiophene-2-carboxaldehyde is often used as a building block in the production of pharmaceuticals, agrochemicals, and other fine chemicals. It is also utilized in the development of chemosensors and fluorescent probes. 4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE has potential applications in various industries and research fields due to its versatile reactivity and properties.

InChI:InChI=1/C5H2BrNO3S/c6-4-1-3(2-8)11-5(4)7(9)10/h1-2H

Upstream product

• 18791-75-8 4-Bromothiophen-2-aldehyde 

Downstream Products

• 911030-16-5 4-[S-([6-methyl-4-(2-trimethylsilanyl-ethoxycarbonylamino)-biphenyl-2-yl]-carbamic acid 2-trimethylsilanyl-ethyl ester)-N-sulfonyl-3-nitrobenzene sulfoximino]-5-methylsulfanyl-thiophene-2-carbamic acid tert-butyl ester 
• 911029-10-2 4-[S-(3-bromophenyl)-N-(3-{N,N-bismethanesulfonylamino}benzene-sulfonyl)sulfoximino]-5-methylsulfanyl-thiophene-2-carboxamidine trifluoroacetate 
• 911030-43-8 4-(3-bromo-benzenesulfoximine)-5-rnethylsulfanyl-thiophene-2-carboamide 
• 911030-39-2 5-bromo-4-(3-bromo-benzenesulfinyl)-thiophene-2-carbonitrile 
• 911030-38-1 5-bromo-4-(3-bromo-phenylsulfanyl)-thiophene-2-carbonitrile 
• 911030-37-0 5-amino-4-(3-bromo-phenylsulfanyl)-thiophene-2-carbonitrile 
• 631911-76-7 4-(3-bromo-benzenesulfinyl)-5-nitro-thiophene-2-carbonitrile 

Relevant articles and documents

DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS

Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols according to formula (I) are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme.

NOVEL THIOPHENE SULFOXIMINES FOR TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS

Disclosed are compounds for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade. Said compounds are of Formula I I or a solvate, hydrate, pharmaceutically acceptable salt, or prodrug thereof; wherein Ra, Rb, and Rc are defined in the specification, as are A Z, Q, R1 and R2.

NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula (I) or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R1, R2, R3, R4 and R7 are defined in the specification, Z is SO or SO2, and Ar is an aromatic or heteroaromatic group as defined herein.