41498-07-1

Usage

Uses

Used in Pharmaceutical Industry:
4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE is used as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs due to its versatile reactivity and properties.
Used in Agrochemical Industry:
In the agrochemical sector, 4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE serves as a key intermediate in the production of agrochemicals, playing a role in the creation of effective and novel pesticides and other agricultural chemicals.
Used in Fine Chemicals Production:
4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE is utilized as a component in the synthesis of various fine chemicals, which are high-purity, high-added-value chemicals used in a wide range of applications, including specialty chemicals and materials.
Used in Chemosensor Development:
4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE is employed in the development of chemosensors, where its unique properties allow for the sensitive and selective detection of specific analytes in various environments.
Used in Fluorescent Probes Research:
4-BROMO-5-NITROTHIOPHENE-2-CARBOXALDEHYDE is also used in the research and development of fluorescent probes, which are essential tools in biological and chemical research for visualizing and tracking specific molecules or processes within complex systems.

InChI:InChI=1/C5H2BrNO3S/c6-4-1-3(2-8)11-5(4)7(9)10/h1-2H

Upstream product

• 18791-75-8 4-Bromothiophen-2-aldehyde 

Downstream Products

• 911030-16-5 4-[S-([6-methyl-4-(2-trimethylsilanyl-ethoxycarbonylamino)-biphenyl-2-yl]-carbamic acid 2-trimethylsilanyl-ethyl ester)-N-sulfonyl-3-nitrobenzene sulfoximino]-5-methylsulfanyl-thiophene-2-carbamic acid tert-butyl ester 
• 911029-10-2 4-[S-(3-bromophenyl)-N-(3-{N,N-bismethanesulfonylamino}benzene-sulfonyl)sulfoximino]-5-methylsulfanyl-thiophene-2-carboxamidine trifluoroacetate 
• 911030-43-8 4-(3-bromo-benzenesulfoximine)-5-rnethylsulfanyl-thiophene-2-carboamide 
• 911030-39-2 5-bromo-4-(3-bromo-benzenesulfinyl)-thiophene-2-carbonitrile 
• 911030-38-1 5-bromo-4-(3-bromo-phenylsulfanyl)-thiophene-2-carbonitrile 
• 911030-37-0 5-amino-4-(3-bromo-phenylsulfanyl)-thiophene-2-carbonitrile 
• 631911-76-7 4-(3-bromo-benzenesulfinyl)-5-nitro-thiophene-2-carbonitrile 

Relevant academic research and scientific papers

DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS

Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols according to formula (I) are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme.

DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS

The invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to compounds that are derivatives of 1 -phenyl-2-pyridinyl alkyl alcohols, methods of preparing such compounds, compositions containing them and therapeutic use thereof.

NOVEL THIOPHENE SULFOXIMINES FOR TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS

Disclosed are compounds for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade. Said compounds are of Formula I I or a solvate, hydrate, pharmaceutically acceptable salt, or prodrug thereof; wherein Ra, Rb, and Rc are defined in the specification, as are A Z, Q, R1 and R2.

Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R1, R2, R3, R4 and R7 are defined in the specification, Z is SO or SO2, and Ar is an aromatic or heteroaromatic group as defined herein.

NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS

Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula (I) or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R1, R2, R3, R4 and R7 are defined in the specification, Z is SO or SO2, and Ar is an aromatic or heteroaromatic group as defined herein.