415696-81-0Relevant academic research and scientific papers
A radical approach towards indolizidine 167B
Corvo, Marta C,Pereira, M.Manuela A
, p. 455 - 458 (2002)
The alkaloids (+)- and (-)-indolizidine 167B were synthesized via radical addition of a carbon radical to a chiral acrylamide. Further cyclization in the presence of BBr3, treatment with 'nickel boride' and stereospecific hydrogenation over palladium/carbon in acetic acid were other key steps in this synthesis.
