41609-02-3Relevant academic research and scientific papers
Synthesis, Structure–Activity Relationship Studies, and ADMET Properties of 3-Aminocyclohex-2-en-1-ones as Chemokine Receptor 2 (CXCR2) Antagonists
Dai, Weiyang,Chen, Wenmin,Debnath, Bikash,Wu, Yong,Neamati, Nouri
, p. 916 - 930 (2018/05/15)
Herein we describe the synthesis and structure–activity relationships of 3-aminocyclohex-2-en-1-one derivatives as novel chemokine receptor 2 (CXCR2) antagonists. Thirteen out of 44 derivatives were found to inhibit CXCR2 downstream signaling in a Tango a
