41634-16-6Relevant academic research and scientific papers
Catalyst-Controlled Transannular Polyketide Cyclization Cascades: Selective Folding of Macrocyclic Polyketides
Raps, Felix C.,F?seke, Vincent C.,H?ussinger, Daniel,Sparr, Christof
supporting information, p. 18390 - 18394 (2020/08/25)
The biomimetic synthesis of aromatic polyketides from macrocyclic substrates by means of catalyst-controlled transannular cyclization cascades is described. The macrocyclic substrates, which feature increased stability and fewer conformational states, were thereby transformed into several distinct polyketide scaffolds. The catalyst-controlled transannular cyclizations selectively led to aromatic polyketides with a defined folding and oxygenation pattern, thus emulating β-keto-processing steps of polyketide biosynthesis.
A Simple Conversion of 2-Methoxynaphthoguinones to 2,3,4,5-Tetrahydronaphthofuran-4,5-diones. Application to the Synthesis of (+/-)-Trypethelones
Guay, Vincent,Brassard, Paul
, p. 1853 - 1857 (2007/10/02)
Structures proposed for trypethelone, O-methyltrypethelone, and O-methyl-8-methoxytrypethelone have been confirmed by synthesis.The required naphthoquinone substrates were prepared regiospecifically in one step by using vinylogous ketene acetals and then converted to the desired products essentially in a novel one-flask procedure.
LAMELLICOLIC ANHYDRIDE, 4-O-CARBOMETHOXYLAMELLICOLIC ANHYDRIDE AND MONOMETHYL 3-CHLOROLAMELLICOLATE, METABOLITES OF VERTICILLIUM LAMELLICOLA
McCorkindale, N. J.,Hutchinson, S. A.,McRitchie, A. C.,Sood, G. R.
, p. 2283 - 2288 (2007/10/02)
The fungus Verticillium lamellicola affords lamellicolic anhydride 1 (5-methyl-2,4,7-trihydroxy-1,8-naphthalic anhydride) together with small amounts of the quinone 2, the carbonate 3 and the chloro compound 4.Selective reactions of the functional groups in these and their derivatives have been used to interrelate these and effect conversion of 1 into 18, the anhydride obtained from Penicillium herquei.
Synthesis of the Fungal Pigment 2,7-Dihydroxy-5-methyl-1,4-naphthoquinone
Cameron, Donald W.,Feutrill, Geoffrey I.,Griffiths, Peter G.
, p. 227 - 229 (2007/10/02)
The title compound has been synthesized and shown to be identical with material derived from the fungus Verticillium lamellicola by comparison of their respective dimethyl ethers
