41652-29-3Relevant academic research and scientific papers
Therapeutically useful N-phenylaniline derivatives
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, (2008/06/13)
There are provided compounds of the general formula STR1 in which Ar represents a phenyl group which is unsubstituted or substituted by a halogen atom or a lower alkyl group, or represents a thienyl group, R1 represents a hydrogen or halogen at
4-(M-benzoylphenyl)butyric acid derivatives
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, (2008/06/13)
Novel butyric acid derivatives of the formula SPC1 Wherein X, X1, X2 and X3 are individually selected from the group consisting of hydrogen, halogen, lower alkyl of 1 to 5 carbon atoms, lower alkoxy of 1 to 5 carbon atoms, lower alkylthio of 1 to 5 carbon atoms, trifluoromethoxy, trifluoromethylthio, trifluoromethyl, OH and dilower alkylamino of 1 to 5 carbon atoms for each alkyl, R is selected from the group consisting of hydrogen, lower alkyl of 1 to 5 carbon atoms, o-carboxyphenyl, 2,3-dihydroxypropyl and -CH2 -CH - CH2 EQU1 wherein P and Q are individually lower alkyl of 1 to 5 carbon atoms, Z and X4 are individually selected from the group consisting of hydrogen and lower alkyl of 1 to 5 carbon atoms and Y is selected from the group consisting of hydrogen and --OH and the dotted line indicates the optional presence of a double bond when Y is hydrogen and when R is hydrogen or o-carboxyphenyl, the salts thereof with a non-toxic pharmaceutically acceptable mineral or organic base, which compounds have anti-inflammatory and analgesic activity and are substantially devoid of ulcerigenic activity and their preparation and novel intermediates formed therein.
