41666-77-7

Basic information

• Product Name: Platinum,(1,2-ethanediamine-kN1,kN2)[propanedioato(2-)-kO1,kO3]-, (SP-4-2)-
• Synonyms: Platinum,(1,2-ethanediamine-N,N')[propanedioato(2-)-O,O']-, (SP-4-2)-;Platinum,(1,2-ethanediamine-kN,kN')[propanedioato(2-)-kO1,kO3]-, (SP-4-2)- (9CI);Propanedioic acid, platinumcomplex;Ethylenediammineplatinum(II) malonate;JM 40;Malonatoethylenediamineplatinum(II);Malpen;NSC 146068;cis-Ethylenediaminemalonatoplatinum(II)
• CAS NO: 41666-77-7
• Molecular Formula: C5H10 N2 O4 Pt
• Molecular Weight: 357.225
• Mol File: 41666-77-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Platinum,(1,2-ethanediamine-kN1,kN2)[propanedioato(2-)-kO1,kO3]-, (SP-4-2)-(CAS DataBase Reference)
• NIST Chemistry Reference: Platinum,(1,2-ethanediamine-kN1,kN2)[propanedioato(2-)-kO1,kO3]-, (SP-4-2)-(41666-77-7)
• EPA Substance Registry System: Platinum,(1,2-ethanediamine-kN1,kN2)[propanedioato(2-)-kO1,kO3]-, (SP-4-2)-(41666-77-7)

Safety Data

• Hazardous Substances Data: 41666-77-7(Hazardous Substances Data)

Upstream product

• 57421-56-4 disilver(I) malonate 
• 14096-51-6 dichloro(ethylenediamine)platinum(II) 
• 141-82-2 malonic acid 
• 23858-10-8 cis-(ethylenediamine)diiodoplatinum(II) 
• 33878-10-3 barium malonate 

Relevant articles and documents

Molecular interaction fields vs. quantum-mechanical-based descriptors in the modelling of lipophilicity of platinum(iv) complexes

We report QSAR calculations using VolSurf descriptors to model the lipophilicity of 53 Pt(iv) complexes with a diverse range of axial and equatorial ligands. Lipophilicity is measured using an efficient HPLC method. Previous models based on a subset of these data are shown to be inadequate, due to incompatibility of whole molecule descriptors between carboxylato and hydroxido ligands. Instead, the interaction surfaces of complexes with various probes are used as independent descriptors. Partial least squares modelling using three latent variables results in an accurate (R2 = 0.92) and robust model (Q2 = 0.87) of lipophilicity, that moreover highlights the importance of size and hydrophobicity terms and the modest relevance of hydrogen bonding.