41689-50-3 Usage
Uses
Used in Research Applications:
(+)-Epiaschantin is used as a research compound to study its hepatotoxic and carcinogenic effects, as well as to investigate potential countermeasures or treatments for liver damage caused by this toxic alkaloid.
Used in Toxicology Studies:
(+)-Epiaschantin is utilized in toxicology studies to understand the mechanisms of its toxicity and to develop methods for detecting and mitigating its harmful effects on human health.
Used in Plant Screening and Identification:
(+)-Epiaschantin serves as a marker for identifying plants that contain this toxic compound, enabling the development of screening methods to prevent exposure and consumption of plants with potentially harmful effects.
Note: Due to the hepatotoxic and carcinogenic nature of (+)-Epiaschantin, it is crucial to handle and consume plants containing (+)-Epiaschantin with extreme caution. Its use in any other applications beyond research and toxicology studies is not recommended.
Check Digit Verification of cas no
The CAS Registry Mumber 41689-50-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,6,8 and 9 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 41689-50:
(7*4)+(6*1)+(5*6)+(4*8)+(3*9)+(2*5)+(1*0)=133
133 % 10 = 3
So 41689-50-3 is a valid CAS Registry Number.
InChI:InChI=1/C22H24O7/c1-23-18-7-13(8-19(24-2)22(18)25-3)21-15-10-26-20(14(15)9-27-21)12-4-5-16-17(6-12)29-11-28-16/h4-8,14-15,20-21H,9-11H2,1-3H3/t14?,15?,20?,21-/m0/s1
41689-50-3Relevant academic research and scientific papers
Chromatography-free “two-pots” asymmetric total synthesis of (+)-sesamin and (+)-aschantin
Hajra, Saumen,Garai, Sujay,Sen, Biswajit
, (2020/09/02)
A gram-scale chromatography-free asymmetric total synthesis of both homo- and heterobiaryl furofuran lignans containing at least one methylenedioxy phenyl unit such as (+)-sesamin and (+)-aschantin is accomplished in “two-pots” from easily accessible enantiopure lactone involving four steps in high overall yields. Steps- and pot economy are the key advantages of the protocol. Additionally, the bromo-functionality of the intermediates is useful for late stage functionalization.
Stereocontrolled total syntheses of optically active furofuran lignans
Inai, Makoto,Ishikawa, Ryo,Yoshida, Naoto,Shirakawa, Nana,Akao, Yusuke,Kawabe, Yusuke,Asakawa, Tomohiro,Egi, Masahiro,Hamashima, Yoshitaka,Kan, Toshiyuki
, p. 3513 - 3521 (2015/11/17)
Plant products (+)-sesamin, (+)-sesaminol, (+)-methylpiperitol, (+)-aschantin, and (+)-5'-hydroxymethylpiperitol were synthesized in a highly stereocontrolled manner through l-proline-catalyzed bifunctional-urea-accelerated cross-aldol reaction, followed by biomimetic construction of the furofuran lignan skeleton through a quinomethide intermediate.
