41716-93-2Relevant academic research and scientific papers
PAF antagonist, 1,4-disubstituted piperazine compounds and production thereof
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, (2008/06/13)
Platelet Activating Factor (PAF) antagonists which comprises the compounds of the formula (I): wherein A is an optionally substituted phenyl or an optionally substituted heterocyclic group; X is methylene group, carbonyl group or thiocarbonyl group; R1, R2 and R3 are independently a lower alkyl group, and their salts are excellent in absorption from the intestinal canal. Among the compounds of the formula (I), those wherein A is an optionally substituted 2,3-dihydro-1-benzoxepin-4--yl group are novel compounds and exhibit excellent PAF antagonism.
PAF antagonist, 1,4-disubstituted piperazine compounds and production thereof
-
, (2008/06/13)
Platelet Activating Factor (PAF) antagonists which comprise the compounds of the formula (I): STR1 wherein A is an optionally substituted phenyl or an optionally substituted heterocyclic group; X is methylene group, carbonyl group or thiocarbonyl group; R1, R2 and R3 are independently a lower alkyl group, and their salts are excellent in absorption from the intestinal canal. Among the compounds of the formula (I), those wherein A is an optionally substituted 2,3-dihydro-1-benzoxepin-4-yl group are novel compounds and exhibit excellent PAF antagonism.
