41743-44-6 Usage
Uses
Ferutinin acts as an agonist for estrogen receptor (ER) α. It also increases calcium permeability of lipid bilayer membranes, mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes.
Check Digit Verification of cas no
The CAS Registry Mumber 41743-44-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,7,4 and 3 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 41743-44:
(7*4)+(6*1)+(5*7)+(4*4)+(3*3)+(2*4)+(1*4)=106
106 % 10 = 6
So 41743-44-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H30O4/c1-14(2)22(25)12-11-21(4)10-9-15(3)13-18(19(21)22)26-20(24)16-5-7-17(23)8-6-16/h5-9,14,18-19,23,25H,10-13H2,1-4H3/t18-,19+,21-,22+/m0/s1
41743-44-6Relevant articles and documents
Hemisynthesis, Antitumoral Effect, and Molecular Docking Studies of Ferutinin and Its Analogues
Safi, Rmi,Rodriguez, Frderic,Hilal, Georges,Diab-Assaf, Mona,Diab, Youssef,El-Sabban, Marwan,Najjar, Fadia,Delfourne, Evelyne
, p. 382 - 397 (2016/03/12)
The natural product ferutinin was shown to act as an agonist to estrogen receptor ERα and agonist/antagonist to ERβ featuring a weak antiproliferative activity toward breast cancer cells. To enhance this activity, ferutinin analogues were synthesized by e