4175-78-4 Usage
Chemical Properties
White to brown crystalline powder
Uses
Different sources of media describe the Uses of 4175-78-4 differently. You can refer to the following data:
1. Used as a building block in material science.1,2
2. 2,5-Dibromothiazole is used in the preparation of arylthiazolylpiperidine derivatives and analogs for use as survival motor neuron (SMN) protein production modulators.
3. Used as a building block in material science.
Check Digit Verification of cas no
The CAS Registry Mumber 4175-78-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,7 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4175-78:
(6*4)+(5*1)+(4*7)+(3*5)+(2*7)+(1*8)=94
94 % 10 = 4
So 4175-78-4 is a valid CAS Registry Number.
InChI:InChI=1/C3HBr2NS/c4-2-1-6-3(5)7-2/h1H
4175-78-4Relevant articles and documents
COURSE OF BROMINATION OF THIAZOLE AND 2-METHYLTHIAZOLE
Gol'dfarb, Ya. L.,Gromova, G. P.,Belen'kii, L. I.
, p. 663 - 666 (1986)
Bromination of thiazole by bromine in the presence of aluminium chloride in neutral solvent or without solvent takes place at the 2-position.Such an orientation contradicts the traditional addition-cleavage mechanism, and agrees with the ylid mechanism of electrophilic substitution. 2-Methylthiazole brominates at the 5-position, and the reaction is impeded in the presence of aluminium chloride; this is due to heterocycle deactivation by complexation with the Lewis acid at the nitrogen atom.
