41781-05-9

Upstream product

• 29770-63-6 1-(α-cyanoisopropyl)-1-nitrocyclohexane 
• 78-82-0 Isobutyronitrile 
• 1165952-91-9 cyclohexa-1,3-diene 
• 108-85-0 1-bromocyclohexane 

Downstream Products

• 143689-08-1 2-cyclohexyl-2-methyl-propylamine 

Relevant academic research and scientific papers

Organometallic Lewis Acids, Part LXII. Chiral Carbonyl-Cyclopentadienyl-Triphenylphosphine-Iron and -Ruthenium Complexes with Tertiary Nitriles [CpM(CO)(PPh3)(N≡C–CR1R2R3)]+ BF4–

A series of tertiary nitriles was synthesized by alkylation of acetonitrile, primary and secondary nitriles, using alkylbromides and sodium amide in liquid ammonia. By reaction of the in situ formed organometallic Lewis acids [CpM(CO)(PPh3)]su

FURANOPYRIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE

Furanopyridine cannabinoid analog compounds of the formula (I) are disclosed. The compounds are useful to modify the activity of CB 1 and CB2 receptors and treat conditions mediated by these receptors.

FURANOPYRIMIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE

Furanopyrimidine cannabinoid analog compounds of the formula I are disclosed. The compounds are useful to modify the activity of CB 1 and CB2 receptors and treat conditions mediated by these receptors.

Pyrimidine Non-Classical Cannabinoid Compounds and Related Methods of Use

Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.

Pyridine Non-Classical Cannabinoid Compounds and Related Methods of Use

wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.

Pyrimidine Classical Cannabinoid Compounds and Related Methods of Use

Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.

Transition metal-free addition of ketones or nitriles to 1,3-dienes

The simpler the better (or going green): The first examples of the catalytic addition of 1,3-dienes to simple ketones or nitriles are described. These reactions can be effected on a kilogram scale, representing the shortest access featuring a perfect atom economy to molecules of interest in the perfume industry. The Royal Society of Chemistry.

Use of Fragmentation Probes in a Study of the Reduction Reactions of 8-B-4 Complexes

The reduction of a number of mechanistic probes with several borate complexes, NaBH4, Li(C2H5)3BH, and lithium dimesityl borohydride, has been shown to occur by both an electron transfer-hydrogen atom abstraction mechanism and a hydride transfer process.Although the electron transfer-hydrogen atom abstraction mechanism can nearly always be detected or be initiated, it is usually only a minor reaction, and only when the reducing agent and/or the substrate is sterically hindered or when the acceptor is a strong oxidizing agent is the homolytic pathway preferred.