41791-77-9Relevant academic research and scientific papers
Generation of Endocyclic Vinyl Carbene Complexes via Gold-Catalyzed Oxidative Cyclization of Terminal Diynes: Toward Naphthoquinones and Carbazolequinones
Shu, Chao,Shi, Chong-Yang,Sun, Qing,Zhou, Bo,Li, Tian-You,He, Qiao,Lu, Xin,Liu, Rai-Shung,Ye, Long-Wu
, p. 1019 - 1025 (2019/01/15)
Carbene cascade reactions involving carbene/alkyne metathesis have attracted much attention over the past decades because this chemistry offers great potential to build complicated cyclic molecules. However, the formed vinyl metal carbenoids in these reactions are limited to exocyclic carbenes, and the generation of endocyclic vinyl carbene complexes remains unexplored. Here, we report an unprecedented gold-catalyzed oxidative cyclization of terminal diynes. Importantly, the generation of endocyclic vinyl carbene complexes was involved in this oxidative cyclization, which is distinctively different from previous protocols. This method allows the facile synthesis of various valuable naphthoquinones and carbazolequinones from readily available diynes under exceptionally mild reaction conditions and features a broad substrate scope and wide functional group tolerance. Moreover, theoretical calculations provide further evidence on the divergent selectivity of this cyclization reaction.
Trinuclear Mn(ii) complex with paramagnetic bridging 1,2,3-dithiazolyl ligands
Sullivan, David J.,Clerac, Rodolphe,Jennings, Michael,Lough, Alan J.,Preuss, Kathryn E.
supporting information, p. 10963 - 10965 (2013/01/15)
The first metal coordination complex of a radical ligand based on the 1,2,3-dithiazolyl heterocycle is reported. 6,7-Dimethyl-1,4-dioxo-naphtho[2,3-d] [1,2,3]dithiazolyl acts as a bridging ligand in the volatile trinuclear Mn(hfac)2-Rad-Mn(hfac)2-Rad-Mn(hfac)2 complex (hfac = 1,1,1,5,5,5-hexafluoroacetylacetonato-). The Mn(ii) and radical ligand spins are coupled anti-ferromagnetically (AF) resulting in an ST = 13/2 spin ground state.
Methylated 2-aryl-1,4-naphtoquinone derivatives with diminished antioxidative activity
Wurm,Schwandt
, p. 531 - 538 (2007/10/03)
2-(3,5-Di-tert-butyl-4-hydroxyphenyl)-3-hydroxy-1,4-naphthoquinone (1) is a selective 5-lipoxygenase (5-LOX) inhibitor possessing high antioxidative activity (AOA). In order to study the question if this activity corresponds to the mechanism of the 5-LOX
Studies on v-triazoles. 9. Antiallergic 4,9-dihydro-4,9-dioxo-1H-naphtho[2,3-d]-v-triazoles
Buckle,Smith,Spicer,Tedder
, p. 714 - 719 (2007/10/02)
A short series of the title compounds was prepared and evaluated for antiallergic activity in the rat passive cutaneous anaphylaxis screen. All but the two N-methylated derivatives were active in this screen by the intravenous route, the most potent being
