4185-53-9Relevant articles and documents
Scalability of a Time- And Cost-Effective Procedure for the Synthesis of Picryl Bromide
Klap?tke, Thomas M.,Dosch, Dominik E.
, p. 2096 - 2098 (2019)
An optimized synthetic procedure for the manufacture of picryl bromide on a 300 g scale is described. Previous procedures had different drawbacks such as two or more separate nitration steps with varying mixed acids, a complicated workup and purification
Chloro- and bromo-demethoxylation of methoxypolynitroaryl systems
Bellamy, Anthony J.,Hudson, P. Nick
, p. 5639 - 5642 (2007/10/03)
Various reagents for effecting halogenodemethoxylation of methoxy substituted polynitrophenyl and -biphenyl systems have been investigated, and the preferred procedures for achieving chloro- and bromo-demethoxylation in high yield have been identified.
Nitrocarbons. 4. Reaction of Polynitrobenzenes with Hydrogen Halides. Formation of Polynitrohalobenzenes
Nielsen, Arnold T.,Chafin, Andrew P.,Christian, Stephen L.
, p. 4575 - 4580 (2007/10/02)
Hexanitrobenzene and pentanitrobenzene in benzene solution react with hydrogen halides (HCl, HBr, HI, but not HF) at 25 deg C to produce high yields of pentanitrohalobenzenes and 2,3,4,6-tetranitrohalobenzenes, respectively.Pentanitrofluorobenzene also reacts readily with HCl to yield 3-chloro-2,4,5,6-tetranitrofluorobenzene, but the other pentanitrohalobenzenes are much less reactive. 1,2,3,5- and 1,2,4,5-tetranitrobenzenes react rapidly with concentrated hydrochloric or hydrobromic acids at reflux to form picryl halides and 1-halo-2,4,5-trinitrobenzenes, respectively; pentanitrotoluene reacts very slowly under these conditions to form 3-halo-2,4,5,6-tetranitrotoluenes in lower yields.The scope and limitations of this regioselective reaction are defined, and comparison is made to related reactions.A mechanism is presented and discussed.