41863-52-9

Basic information

• Product Name: tert-butyl (1-hydrazinyl-1-oxopropan-2-yl)carbaMate
• Synonyms: N-[(1S)-2-hydrazino-1-methyl-2-oxoethyl]carbamic acid tert-butyl ester;N-[(1S)-2-hydrazino-2-keto-1-methyl-ethyl]carbamic acid tert-butyl ester;tert-butyl (2-hydrazino-1-methyl-2-oxoethyl)carbamate;tert-butyl N-[(1S)-2-hydrazino-1-methyl-2-oxo-ethyl]carbamate;tert-butyl N-[(2S)-1-hydrazinyl-1-oxo-propan-2-yl]carbamate;tert-butyl N-[(2S)-1-hydrazinyl-1-oxopropan-2-yl]carbamate;tert-butyl (1-hydrazinyl-1-oxopropan-2-yl)carbaMate;tert-Butyl N-[(1S)-1-(hydrazinecarbonyl)-ethyl]carbamate
• CAS NO: 41863-52-9
• Molecular Formula: C₈H₁₇N₃O₃
• Molecular Weight: 203.23888
• Mol File: 41863-52-9.mol
• Article Data: 29

Chemical Properties

• Appearance: /
• CAS DataBase Reference: tert-butyl (1-hydrazinyl-1-oxopropan-2-yl)carbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (1-hydrazinyl-1-oxopropan-2-yl)carbaMate(41863-52-9)
• EPA Substance Registry System: tert-butyl (1-hydrazinyl-1-oxopropan-2-yl)carbaMate(41863-52-9)

Safety Data

• Hazardous Substances Data: 41863-52-9(Hazardous Substances Data)

Upstream product

• 28875-17-4 (S)-N-(tert-butoxycarbonyl)alanine methyl ester 
• 7803-57-8 hydrazine hydrate 
• 15761-38-3 L-N-Boc-Ala 
• 530-62-1 1,1'-carbonyldiimidazole 
• 119706-04-6 BOC-Ala-OBg 
• 144800-33-9 Boc-Ala-OAbc 
• 113707-01-0 Boc-Ala-OCet 
• 51814-53-0 N-tert-butoxycarbonyl-L-alanine ethyl ester 
• 57400-52-9 1-Butoxycarbonyl-L-alanin-N'-4-picolyloxycarbonylhydrazid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 91103-47-8 N-(tert-butoxycarbonyl)-D-alanine methyl ester 

Downstream Products

• 1452467-82-1 tert-butyl [(2R)-1-(2-{[(2S,5R)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]oct-2-yl]carbonyl}hydrazinyl)-1-oxopropan-2-yl]carbamate 
• 1429181-99-6 (S)-tert-butyl (1-(2-benzoylhydrazinyl)-1-oxopropan-2-yl)carbamate 
• 1429182-00-2 (S)-tert-butyl (1-(5-phenyl-1,3,4-thiadiazol-2-yl)ethyl)carbamate 
• 1357304-07-4 C₂₁H₃₄N₄O₇S 
• 1357304-19-8 N-(Boc)-alaninyl-azasulfurylglycinyl-D-phenylalanine tert-butyl ester 
• 1357304-18-7 C₂₁H₃₄N₄O₇S 

Relevant articles and documents

Synthesis of 5 H -Pyrrolo[3,4- b ]pyrazine-Based Peptidomimetics

A range of 5H-pyrrolo[3,4-b]pyrazine-based peptidomimetics were designed, and their efficient synthesis starting from 5-imino-5H-pyrrolo[3,4-b]pyrazin-7-amine by subsequent interaction with N-protected amino acid hydrazides and amino acid esters with N,N-carbonyldiimidazole as the coupling agent was elaborated.

Amino Acid Functionalized Organotin Trichlorides and Their Tin Sulfide Clusters

We present a new synthesis of functionalized tin sulfide clusters via organotin trichlorides with boc-protected amino acids (RAAcSnCl3). In this work we used non-polar (alanine, valine, leucine, phenylalanine and methionine), polar/neutral (serine and tyrosine) and basic (histidine) amino acids. We obtained single crystals from a Boc-protected valine derivative of the originally used organotin trichloride R1SnCl3 [R1 = CMe2CH2C(O)Me] and determined its structure by means of X-ray diffraction. A subsequent reaction with sulfide sources led to a variety of respective cluster structures. By using either (Me3Si)2S or Na2S, the reaction product turns out to be the defect-heterocubane cluster [(RAAcSn)3S4Cl] or the “doppeldecker”-type cluster [(RAAcSn)4S6], respectively, according to 119Sn NMR spectroscopy.

1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES

The present invention relates to 1,3-thiazol-2-yl substituted benzamide compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neurogenic disorder, as a sole agent or in combination with other active ingredients.