41875-18-7Relevant academic research and scientific papers
Structure-based design and synthesis of covalent-reversible inhibitors to overcome drug resistance in EGFR
Basu, Debjit,Richters, André,Rauh, Daniel
, p. 2767 - 2780 (2015)
The clinical success of covalent kinase inhibitors in the treatment of EGFR-dependent non-small cell lung cancer (NSCLC) has rejuvenated the appreciation of reactive small molecules. Acquired drug resistance against first-line EGFR inhibitors remains the
