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4'-N-Piperidinophenyl acetylene, also known as 4'-N-piperidinophenyl-1-ethynyl-benzene, is an organic compound that features a piperidine ring and a phenylacetylene group. It is recognized for its versatile reactivity and functional group arrangement, making it a valuable building block in organic synthesis. 4'-N-Piperidinophenyl acetylene has garnered attention in medicinal chemistry for its potential therapeutic applications, particularly in the treatment of diseases such as cancer and neurological disorders. Furthermore, its utility extends to material science, where it is explored as a precursor in the development of polymers and advanced materials.

41876-66-8

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41876-66-8 Usage

Uses

Used in Pharmaceutical Drug Synthesis:
4'-N-Piperidinophenyl acetylene is used as a key intermediate in the synthesis of pharmaceutical drugs for its ability to be readily incorporated into complex molecular structures. Its unique structural features allow for the creation of new drug candidates with potential therapeutic benefits.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 4'-N-Piperidinophenyl acetylene is utilized as a research compound for exploring its potential as a therapeutic agent. It is studied for its possible applications in treating various diseases, including cancer and neurological disorders, due to its interaction with biological targets and pathways.
Used in Material Science Research:
4'-N-Piperidinophenyl acetylene is used as a precursor in material science for its potential in synthesizing polymers and advanced materials. Its structural properties make it a candidate for developing new materials with specific properties for various applications.
Used in Organic Synthesis:
As a building block in organic synthesis, 4'-N-Piperidinophenyl acetylene is used for creating a wide range of organic compounds. Its reactivity and functional group arrangement facilitate the formation of diverse chemical entities for use in various industries, including pharmaceuticals, agrochemicals, and specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 41876-66-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,8,7 and 6 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 41876-66:
(7*4)+(6*1)+(5*8)+(4*7)+(3*6)+(2*6)+(1*6)=138
138 % 10 = 8
So 41876-66-8 is a valid CAS Registry Number.
InChI:InChI=1/C13H15N/c1-2-12-6-8-13(9-7-12)14-10-4-3-5-11-14/h1,6-9H,3-5,10-11H2

41876-66-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-ethynylphenyl)piperidine

1.2 Other means of identification

Product number -
Other names 4'-N-Piperidinophenylacetylene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:41876-66-8 SDS

41876-66-8Relevant academic research and scientific papers

COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING

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Paragraph 0397, (2020/10/20)

The present disclosure relates to compounds, pharmaceutical compositions comprising such compounds, and use of such compounds in methods of treatment or in medicaments for treatment of inflammatory diseases and certain neurological disorders that are related to inflammatory signaling processes, including but not limited to misfolded proteins.

Synthesis and electrogenerated chemiluminescence of donor-substituted phenylquinolinylethynes and phenylisoquinolinylethynes: Effect of positional isomerism

Elangovan, Arumugasamy,Yang, Shu-Wen,Lin, Jui-Hsien,Kao, Kuo-Ming,Ho, Tong-Ing

, p. 1597 - 1602 (2007/10/03)

In furtherance of our research on the design, synthesis and study of electrogenerated chemiluminescence (ECL) of new donor substituted phenylquinolinylethynes, we report here more new series with the aim of studying the effect of positional isomerism on their overall photophysical properties with a special focus on ECL. For this study we have chosen 2-, 3-, and 4-(p-substituted phenyl)ethynylquinolines, and 1- and 4-(p-substituted phenyl)ethynylisoquinolines. These ethynes were synthesized in good yields by modified Sonogashira coupling of the corresponding terminal alkyne with the respective haloquinolines. The photophysical properties and ECL were studied in acetonitrile solvent and the various results are discussed.

First synthesis and electrogenerated chemiluminescence of novel p-substituted phenyl-2-quinolinylethynes

Elangovan, Arumugasamy,Chen, Ting-Yu,Chen, Chih-Yuan,Ho, Tong-Ing

, p. 2146 - 2147 (2007/10/03)

A series of p-substituted phenyl-2-quinolinylethynes as blue-green emitters were synthesized using a modified Sonogashira coupling reaction and their electrogenerated chemiluminescence properties are reported.

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