418773-88-3

Basic information

• Product Name: AKOS B023223
• Synonyms: ART-CHEM-BB B023223;CHEMBRDG-BB 5536019;AKOS B023223;(2,3-DIMETHOXY-BENZYL)-ISOPROPYL-AMINE;UKRORGSYN-BB BBV-119242;(2,3-dimethoxybenzyl)isopropylamine(SALTDATA: HCl);[(2,3-dimethoxyphenyl)methyl](propan-2-yl)amine hydrochloride
• CAS NO: 418773-88-3
• Molecular Formula: C12H19NO2
• Molecular Weight: 209.28
• Mol File: 418773-88-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 275.1°C at 760 mmHg
• Flash Point: 115.3°C
• Appearance: /
• Density: 0.985g/cm³
• Vapor Pressure: 0.00521mmHg at 25°C
• Refractive Index: 1.495
• PKA: 9.29±0.19(Predicted)
• CAS DataBase Reference: AKOS B023223(CAS DataBase Reference)
• NIST Chemistry Reference: AKOS B023223(418773-88-3)
• EPA Substance Registry System: AKOS B023223(418773-88-3)

Safety Data

• Hazardous Substances Data: 418773-88-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H19NO2/c1-9(2)13-8-10-6-5-7-11(14-3)12(10)15-4/h5-7,9,13H,8H2,1-4H3

Upstream product

• 86-51-1 2,3-dimethyoxybenzaldehyde 

Relevant articles and documents

Catalytic Asymmetric Synthesis of N-Chiral Amine Oxides

Direct asymmetric synthesis of N-chiral amine oxides was accomplished (up to 91:9 e.r.) by means of a bimetallic titanium catalyst. A hydroxy group situated at the γ-position of the N stereocenter enables the desired N-oxidation through dynamic kinetic resolution of the trivalent amine substrates. The method was further extended to the kinetic resolution of racemic γ-amino alcohols with a preexisting stereocenter, giving an important class of enantioenriched (up to 99.9:0.1 e.r.) building blocks that are otherwise difficult to synthesize.