41907-02-2

Upstream product

• 41806-25-1 4-chloro-α-phenoxyacetophenone 
• 1774-47-6 trimethylsulfoxonium iodide 

Downstream Products

• 161498-34-6 2-Bromo-1-(4-chloro-phenyl)-2-[5-(2-hydroxy-phenyl)-4-phenylamino-4H-[1,2,4]triazol-3-ylsulfanyl]-2-phenoxy-ethanone 
• 161498-35-7 2-Bromo-1-(4-chloro-phenyl)-2-[5-(4-hydroxy-phenyl)-4-phenylamino-4H-[1,2,4]triazol-3-ylsulfanyl]-2-phenoxy-ethanone 
• 161498-36-8 2-Bromo-1-(4-chloro-phenyl)-2-(5-methyl-4-phenylamino-4H-[1,2,4]triazol-3-ylsulfanyl)-2-phenoxy-ethanone 
• 161498-67-5 1-(4-Chloro-phenyl)-2-phenoxy-2-(5-phenyl-4-phenylamino-4H-[1,2,4]triazol-3-ylsulfanyl)-ethanone 
• 161498-68-6 1-(4-Chloro-phenyl)-2-[5-(2-hydroxy-phenyl)-4-phenylamino-4H-[1,2,4]triazol-3-ylsulfanyl]-2-phenoxy-ethanone 
• 161498-69-7 1-(4-Chloro-phenyl)-2-[5-(4-hydroxy-phenyl)-4-phenylamino-4H-[1,2,4]triazol-3-ylsulfanyl]-2-phenoxy-ethanone 
• 161498-70-0 1-(4-Chloro-phenyl)-2-(5-methyl-4-phenylamino-4H-[1,2,4]triazol-3-ylsulfanyl)-2-phenoxy-ethanone 

Relevant academic research and scientific papers

1,3-heterocyclic-substituted alkane

A 2-propanol derivative of the formula I, wherein R1 and R5, which may be the same or different, are each a triazolyl, imidazolyl, pyridyl or pyrimidinyl radical; R2, R3 and R4, which may be the same or different, are each a hydrogen atom, a 1-6C alkyl, halogenoalkyl or alkoxy radical, a 3-8C cycloalkyl radical, or a phenyl, naphthyl, phenoxy, naphthyloxy or phenyl (1-6C alkyl) radical, in each of which the aryl group optionally bears one or more substituents selected from halogen atoms, amino, carboxamido, cyano and nitro radicals, 1-6C alkyl, halogenoalkyl, alkoxy, halogenoalkoxy and alkylamino radicals, 3-8C cycloalkyl radicals, di(1-6C alkyl)amino radicals and 2-6C alkoxycarbonyl radicals; R6 is a phenyl or naphthyl radical optionally bearing one or more substituents as defined above; X is a direct bond, an alkylene, alkenylene or alkynylene radical, or an oxyalkylene or thioalkylene radical wherein respectively the oxygen or sulphur atom is bonded to R6 or a phenylalkylene radical in which the phenyl group bears one or more substituents as defined above for R6 ; and Y is a hydrogen or halogen atom, a hydroxy, cyano or carbamoyl radical, or a phenyl(1-6C alkoxy) radical in which the phenyl group bears one or more substituents as defined above for R6 ; provided that, when Y is a cyano or carbamoyl radical, neither R2, R3 nor R4 may be an alkoxy or aryloxy radical, and either R2 is a hydrogen atom, or R3 and R4 are both hydrogen atoms; and provided that, when R1 and R5 are each a 1,2,4-triazol-1-yl radical, R2 is hydrogen and Y is a hydroxy radical, R3 and R4 may not be hydrogen or methyl when X is a direct bond, and R3 and R4 may not be hydrogen when X is a methylene radical; and for those compounds which contain a basic nitrogen atom, the pharmaceutically acceptable acid additon salts thereof.