41908-14-9Relevant academic research and scientific papers
New reactivity patterns of copper(I) and other transition metal NHC complexes: application to ATRC and related reactions
Bull, James A.,Hutchings, Michael G.,Luján, Cristina,Quayle, Peter
, p. 1352 - 1356 (2008/09/18)
Pre-formed transition metal-NHC complex is shown to be an effective catalyst for Atom Transfer Radical Cyclisation (ATRC) reactions.
An unusual decarboxylative benzannulation and biaryl formation during copper(I)-promoted halogen atom transfer radical cyclization of 2-allylaryl trichloroacetates
Ram, Ram N.,Tittal, Ram K.,Upreti, Shailesh
, p. 7994 - 7997 (2008/03/14)
CuCl/bpy-promoted halogen atom transfer radical cyclization of 2-allylaryl trichloroacetates in refluxing benzene gave benzannulated chloroarenes and benzannulated symmetrical biaryls along with reductive dehalogenation products. The unusual decarboxylative benzannulation and biaryl formation might be explained by a further intramolecular radical addition on the benzene ring of the eight-membered lactone intermediate, initially formed through 8-endo-trig halogen atom transfer radical cyclization, followed by decarboxylation, radical dimerization and dehydrochlorination reactions.
A remarkably simple and efficient benzannulation reaction
Bull, James A.,Hutchings, Michael G.,Quayle, Peter
, p. 1869 - 1872 (2008/03/12)
(Chemical Equation Presented) On a short fuse: Although fused aromatic rings are common structural motifs in natural products, there are relatively few direct methods for the preparation of such systems from acyclic precursors. An atom-transfer radical cyclization carried out under microwave (MW) irradiation has now been developed which gives rapid access to functionalized aromatic compounds from readily available starting materials (see scheme).
PROCESS FOR SYNTHESIS OF AROMATIC COMPOUNDS
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Page/Page column 12; 14, (2008/06/13)
The present invention refers to a process for preparing a compound of the formula (I) wherein R denotes an organic radical which, together with the two carbon atoms to which it is bonded, forms a carbocyclic or heterocyclic ring; R1, R2, R3 and X, independently, denote hydrogen, halogen, nitro, cyano or an organic radical; or R1 and R2 or R2 and R3, together with the carbon atoms to which they are bonded, form a ring; which comprises exposing a compound of the formula (II) wherein R1, R2, R3 and X are defined as given above and Y and Z, independently, have one of the meanings of X; to an energy source in the presence of a catalyst system.
