41938-50-5Relevant academic research and scientific papers
Pd-catalyzed oxidative homocoupling of arylboronic acids in WEPA: A sustainable access to symmetrical biaryls under added base and ligand-free ambient conditions
Appa, Rama Moorthy,Lakshmidevi, Jangam,Naidu, Bandameeda Ramesh,Venkateswarlu, Katta
, (2021)
Symmetrical and unsymmetrical biaryls comprises a diverse class of biologically eloquent organic compounds. We herein report, a quick and eco-friendly protocol for the synthesis of biaryls by an oxidative (aerobic) homocoupling of arylboronic acids (ABAs) using Pd(OAc)2 in water extract of pomogranate ash (WEPA) as an efficient agro-waste(bio)-derived aqueous (basic) media. The reactions were executed at ambient aerobic conditions in the absence of external base and ligand to result symmetrical biaryls in excellent yields. The use of renewable media with an effective exploitation of waste, short reaction times, excellent yields of products, easy separation of the products, unnecessating the external base, oxidant, ligand or volatile organic solvents and ambient reaction conditions are the vital insights of the present protocol.
Aerobic homocoupling of arylboronic acids catalysed by copper terephthalate metal-organic frameworks
Puthiaraj, Pillaiyar,Suresh, Palaniswamy,Pitchumani, Kasi
, p. 2865 - 2875 (2014/05/06)
Copper terephthalate MOF is utilised as an environmentally benign, efficient and reusable heterogeneous catalyst to effect the aerobic homocoupling of arylboronic acids yielding the corresponding symmetrical biphenyls under mild reaction conditions. This method tolerates various substituents present in arylboronic acids such as halogens, cyano and nitro groups. The catalytic performance has been compared with that of other copper based MOFs namely MOF-101, [Cu(pdc)2]NH2Me2, [Cu 2(ndc)2ted]n and [Cu(H2L)] n as well as with other copper salt catalysts. Sheldon test confirmed the heterogeneity of the catalyst, which can be reused under optimized conditions with only a minor loss in its activity. A mechanism for the homocoupling reaction is also proposed. The simplicity of catalyst preparation, its stability, substrate selectivity, easy recovery and regeneration designate possible utilization of this catalytic system in a multitude of catalytic reactions and industrial processes. the Partner Organisations 2014.
