41940-38-9Relevant academic research and scientific papers
Reaction of 3-Acetyltropolone and its Methyl Ethers with Hydroxylamine. Formation of 8H-Cycloheptisoxazol-8-one and 8H-Cycloheptisoxazol-8-one
Yasunori, Sudoh,Zhong-Tian, Jin,Kimiaki, Imafuku,Hisashi, Matsumura
, p. 525 - 528 (2007/10/02)
The reaction of 3-acetyltropolone (1) with hydroxylamine under the acidic condition gave 3-methyl-8H-cycloheptisoxazol-8-one (4) and its oxime (5), and under the neutral condition gave 4 and 3-acetyltropolone oxime (6).The reaction of 3-acetyl-2-methoxytropone (2a) with hydroxylamine under the acidic condition gave 4, 5, and 4-methyl-1H-2,3-benzoxazin-1-one (7), and under the neutral condition gave 4, 7, 3-methyl-8H-cycloheptisoxazol-8-one (8), and its oxime (9).The reaction of 7-acetyl-2-methoxytropone (2b) with hydroxylamine under acidic condition gave 4 and 5, and under the neutral condition gave 5, 7, and 9.
