41945-37-3

Basic information

• Product Name: 3-bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine
• Synonyms: 3-bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine
• CAS NO: 41945-37-3
• Molecular Formula: C8H8BrN3
• Molecular Weight: 226.0732
• Mol File: 41945-37-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.67g/cm³
• Refractive Index: 1.687
• CAS DataBase Reference: 3-bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine(41945-37-3)
• EPA Substance Registry System: 3-bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidine(41945-37-3)

Safety Data

• Hazardous Substances Data: 41945-37-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H8BrN3/c1-5-3-6(2)12-8(11-5)7(9)4-10-12/h3-4H,1-2H3

Upstream product

• 128-08-5 N-Bromosuccinimide 
• 35149-38-3 5,7-Dimethyl-pyrazolo<1,5-a>pyrimidin 

Relevant articles and documents

3 Substituted 5,7 dimethylpyrazolo[1,5 α]pyrimidines, 3',5' cyclic AMP phosphodiesterase inhibitors. 1

A series of 3 substituted 5,7 dimethylpyrazolo[1,5 α]pyrimidines were synthesized and evaluated for their ability to inhibit the enzyme 3',5' cyclic AMP phosphodiesterase that was isolated and purified from rabbit kidney, rabbit lung, and beef heart. The 3 bromo, 3 chloro, 3 iodo, and 3 acetyl derivatives were found to be more potent than theophylline in their ability to inhibit these 3',5' cAMP phosphodiesterases.

3,5,7-TRISUBSTITUTED PYRAZOLO[1,5-a]PYRAMIDINES

3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines are disclosed of the general formula wherein R1 is CF3 or C1-C9 alkyl; R2 is CF3 or C1-C9 alkyl; and R3 is halogen. Such compounds are useful as inhibitors of 3',5'-cyclic AMP phosphodiesterase enzyme