419564-47-9Relevant academic research and scientific papers
Mn(III)-based oxidative free-radical cyclizations of alkenyl Meldrum's acids
Snider, Barry B.,Smith, Rachel B.
, p. 25 - 34 (2002)
Oxidative cyclization of unsaturated Meldrum's acids can be carried out at temperatures as low as -30°C. The rate-determining step is cyclization of the enolate to the alkene (11 to 14 and 15) rather than enolization, which is the rate-determining step with dimethyl 4-pentenylmalonate (1). While cyclization of 1 gives mainly cyclopentanes, cyclization of Meldrum's acids provides a versatile route to cyclohexenes.
