419573-14-1Relevant articles and documents
A new silyl ether-type linker useful for the automated synthesis of oligonucleotides having base-labile protective groups
Kobori, Akio,Miyata, Kenichi,Ushioda, Masatoshi,Seio, Kohji,Sekine, Mitsuo
, p. 16 - 17 (2007/10/03)
A new silyl-type linker for the automated solid-phase synthesis of oligodeoxynucleotides was developed. A hydrosilane-type reagent for introduction of the silyl linker was synthesized in an overall yield of 50% from 1,4-dibromobenzene. By using this linke