4197-24-4

Basic information

• Product Name: CARBOL FUCHSIN
• Synonyms: AFB STAIN;4-[(4-amino-m-tolyl)(4-iminocyclohexa-2,5-dien-1-ylidene)methyl]-o-toluidine monohydrochloride;CarbolFuchsinStrongStainingSolution;CarbolFuchsin,DiluteSolutionForGramStai;CarbolFuchsinDiluteStainingSolution;CarbolFuchsin(Zeihl-Neelsen)Solution;CARBOL FUCHSIN FOR MICROSCOPY;Carbol Fuchsin, pure
• CAS NO: 4197-24-4
• Molecular Formula: C26H26ClN3O
• Molecular Weight: 431.96
• EINECS: 224-086-6
• Product Categories: Hematology and Histology;Histology Special Stains;Staining Solutions for Acid Fast StainingMicroscopy Reagents and Kits;Staining Solutions for Simple Stains of Bacteria;Microscopy Reagents and Kits;Staining Solutions;C;Stains and Dyes;Stains&Dyes, A to
• Mol File: 4197-24-4.mol

Chemical Properties

• Boiling Point: 593.8 °C at 760 mmHg
• Flash Point: 58 °C
• Appearance: Dark green/Crystalline Powder
• Density: 0.99 g/mL at 20 °C
• Vapor Density: 3.24 (vs air)
• Vapor Pressure: 3.69E-13mmHg at 25°C
• Water Solubility: Very soluble
• CAS DataBase Reference: CARBOL FUCHSIN(CAS DataBase Reference)
• NIST Chemistry Reference: CARBOL FUCHSIN(4197-24-4)
• EPA Substance Registry System: CARBOL FUCHSIN(4197-24-4)

Safety Data

• Hazard Codes: T,C
• Statements: 45-36/38-68-34-20/21/22-48/20/21/22-23/24/25
• Safety Statements: 53-36/37-45-36/37/39-26
• RIDADR: UN 2924 3/PG 3
• WGK Germany: 3
• F: 8-9-23
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 4197-24-4(Hazardous Substances Data)

Usage

Uses

Used in Microbiology:
CARBOL FUCHSIN is used as a staining agent for the detection and identification of microorganisms, particularly for the staining of acid-fast bacteria such as Mycobacterium tuberculosis. Its chemical properties allow it to bind to the lipid-rich cell walls of these bacteria, providing a distinct color contrast for easier visualization under a microscope.
Used in Histology:
In histology, CARBOL FUCHSIN is employed as a counterstain to enhance the contrast and visualization of tissue structures. It is often used in conjunction with other dyes, such as hematoxylin, to provide a clear and detailed representation of cellular components and extracellular matrix.
Used in Textile Industry:
CARBOL FUCHSIN is used as a dye in the textile industry for the coloration of fabrics. Its ability to bind to fibers and provide a deep, vibrant color makes it a popular choice for various applications, including the production of clothing, upholstery, and other textile products.
Used in Analytical Chemistry:
In analytical chemistry, CARBOL FUCHSIN is utilized as a reagent for the detection and quantification of certain chemical compounds. Its unique chemical properties enable it to react with specific substances, allowing for accurate measurement and analysis in various laboratory settings.

Indications

Carbol-fuchsin solution (Castellani’s paint) is an aqueous alcohol-acetone solution containing phenol (4.5 g/100 mL), resorcinol (10 g/100 mL), and basic fuschin (300 mg/100 mL). The basic fuschin appears as a dark purple liquid that appears red on the skin and can stain. It has local anesthetic, bactericidal, and fungicidal properties. It has also been reported to stimulate granulation and epithelization. It is applied topically in the treatment of subacute and chronic superficial fungal infection. It is particularly effective in intertriginous areas. Carbol-Fuschin is poisonous when ingested and is treated in the same manner as phenol or resorcinol poisoning.

InChI:InChI=1/C21H21N3.ClH/c1-13-11-16(5-9-19(13)23)21(15-3-7-18(22)8-4-15)17-6-10-20(24)14(2)12-17;/h3-12,23H,22,24H2,1-2H3;1H/b21-16-,23-19?;