4197-78-8 Usage
General Description
The chemical 2-isobutylbenzene-1,4-diol, also known as ibuprofenol, is a derivative of the common pain reliever ibuprofen. It is a white crystalline powder that is slightly soluble in water and has a melting point of 73-76 degrees Celsius. It is primarily used as an intermediate in the synthesis of ibuprofen and other pharmaceuticals. The compound has analgesic, antipyretic, and anti-inflammatory properties, similar to ibuprofen, and may have potential applications in the treatment of pain and inflammation. It is important to handle and store 2-isobutylbenzene-1,4-diol with care, following proper safety protocols and guidelines.
Check Digit Verification of cas no
The CAS Registry Mumber 4197-78-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,9 and 7 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 4197-78:
(6*4)+(5*1)+(4*9)+(3*7)+(2*7)+(1*8)=108
108 % 10 = 8
So 4197-78-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O2/c1-7(2)5-8-6-9(11)3-4-10(8)12/h3-4,6-7,11-12H,5H2,1-2H3
4197-78-8Relevant articles and documents
Chiral cobalt(II) complex catalyzed Friedel-Crafts aromatization for the synthesis of axially chiral biaryldiols
Xu, Chaoran,Zheng, Haifeng,Hu, Bowen,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming
supporting information, p. 9741 - 9744 (2017/09/07)
An efficient atroposelective synthesis of axially chiral biaryldiols via asymmetric Friedel-Crafts aromatization between p-quinones and 2-naphthols was developed. A chiral cobalt(ii) complex of N,N′-dioxide enabled the process to generate axially chiral biaryldiols in up to 98% yield and 95% ee. A large range of substituents at different positions of p-quinones and 2-naphthols was tolerable. The configuration of the product and the chiral N,N′-dioxide-Co(ClO4)2 catalyst was identified by X-ray crystal diffraction analysis and a possible catalytic model was suggested.
