4199-31-9Relevant articles and documents
METHODS FOR ENGINEERING THERAPEUTICS AND USES THEREOF
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Page/Page column 6; 8, (2021/05/15)
The disclosed subject matter provides for genetically modified cells, e.g, fungal cells, that autonomously generates and/or secretes one or more therapeutic molecules, e.g, therapeutic peptides, therapeutic proteins or small therapeutic molecules, in situ. In certain embodiments, the present disclosure provides genetically-engineered fungal cells that generate and secrete tetracycline and analogues thereof.