42010-79-7Relevant academic research and scientific papers
Cobalt-catalyzed arylation or benzylation of 2-chloro-4,6-dimethoxy-1,3,5- triazine
Begouin, Jeanne Marie,Claudel, Stephanie,Gosmini, Corinne
experimental part, p. 3192 - 3194 (2010/04/04)
A variety of functionalized aryl bromides or benzyl chlorides were coupled with 2-chloro-4,6-dimethoxy-1,3,5-trazine in good yields by a one-step procedure via cobalt catalysis. Georg Thieme Verlag Stuttgart.
Organometallic alkylation of 2-chloro-4,6-dimethoxy-1,3,5-triazine: A study
Samaritani, Simona,Signore, Giovanni,Malanga, Corrado,Menicagli, Rita
, p. 4475 - 4483 (2007/10/03)
The reactivity of 2-chloro-4,6-dimethoxy-1,3,5-triazine (1) has been investigated in Pd- or Ni-catalyzed cross-coupling processes with organostannanes, Grignard reagents, organoalanes and organozinc halides. All organometallic reagents considered form new C-C bonds on the heteroaromatic ring and afford the corresponding 2-alkyl-4,6-dimethoxy-1,3,5-triazines in moderate to very good yields. The collected data allows the choice of the alkylating agent as well as the experimental conditions depending on the residue to transfer.
In vitro cytotoxic activities of 2-alkyl-4,6-diheteroalkyl-1,3,5-triazines: New molecules in anticancer research
Menicagli, Rita,Samaritani, Simona,Signore, Giovanni,Vaglini, Francesca,Dalla Via, Lisa
, p. 4649 - 4652 (2007/10/03)
The cytotoxic activities of new 2-alkyl-4,6-dihetero-(N,O)alkyl-1,3,5- triazines toward selected tumor cell lines have been evaluated, and for the first time, the potential of 2-alkyl-4,6-dialkoxy-1,3,5-triazines has been shown.
