420132-18-9

Upstream product

• 470700-29-9 N-(2,2-dimethoxyethyl)-N-tosylbuta-2,3-dien-1-amine 
• 98-59-9 p-toluenesulfonyl chloride 
• 58754-95-3 N-(2,2-dimethoxyethyl)-p-toluenesulfonamide 
• 55022-46-3 4-methyl-N-prop-2-ynylbenzenesulfonamide 
• 317842-46-9 N-(2-hydroxyethyl)-4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 
• 317842-43-6 N-(2,2-dimethoxyethyl)-4-methyl-N-(prop-2-yn-1-yl)benzenesulfonamide 

Downstream Products

• 944417-97-4 (Z)-N-N-(buta-2,3-dien-1-yl)-N-(2-(hydroxyimino)ethyl)-4-methylbenzenesulfonamide 
• 1015445-22-3 (3S,4S)-1-[(4-methylphenyl)sulfonyl]-4-(1-phenylethenyl)-3-pyrrolidinol 

Relevant academic research and scientific papers

Copper-catalyzed cycloisomerization of unactivated allene-tethered O-propargyl oximes: A domino reaction sequence toward the synthesis of hexahydropyrrolo[3,4- b]azepin-5(4 H)-ones

A novel copper-catalyzed cycloisomerization of unactivated allene-tethered O-propargyl oximes has been developed for the synthesis of hexahydropyrrolo[3,4-b]azepin-5(4H)-ones. This one-pot domino reaction proceeds via a [2,3]-sigmatropic rearrangement, a

Thiocyanate radical mediated dehydration of aldoximes with visible light and air

We developed a new means of activating aldoximes by an in situ generated thiocyanate radical from ammonium thiocyanate and molecular oxygen at room temperature. With a catalytic amount of organic dye aizenuranine as the photocatalyst, the dehydration of aldoximes proceeds smoothly under visible light irradiation, providing a simple to handle, excellent functional group tolerance, and metal-free protocol for a wide range of nitriles.

Synthesis of α-methylene-γ-butyrolactones: Ru-catalyzed cyclocarbonylation of allenyl aldehydes and allenyl ketones

An efficient route to α-methylene-γ-lactones involves the Ru-catalyzed [2+2+1] cycloadditions of allenyl aldehydes and ketones with CO (see scheme; n = 1, 2; R = H, CH3; X = NTs, O, C(CO2Et)2; Ts = toluene-4-sulfonyl). The