420132-32-7Relevant academic research and scientific papers
Diastereoselective Reductive Cyclization of Allene-Tethered Ketoamines via Copper-Catalyzed Cascade Carboboronation and Protodeborylation
Ashraf, Muhammad Awais,Tambe, Shrikant D.,Cho, Eun Jin
, p. 683 - 690 (2021)
A copper-catalyzed cascade process has been developed for the synthesis of 3-hydroxypyrrolidine derivatives in a highly diastereoselective manner. The reaction proceeded via borylative allyl copper intermediate formation from allenes; the intermediate underwent intramolecular diastereoselective cyclization followed by cascade copper-catalyzed protodeborylation, to give 3-hydroxypyrrolidines. This method could be extended to the synthesis of six-membered piperidine analogs. A series of control experiments were carried out to confirm the Cu-catalyzed facile protodeborylation of borylated homoallylic alcohols at room temperature.
Mercury(II) triflate-catalyzed cycloisomerization of allenynes to allenenes
So, Hee Sim,Sang, Ick Lee,Seo, Junhyeok,Young, Keun Chung
, p. 9818 - 9821 (2007)
(Chemical Equation Presented) Cycloisomerizations of allenynes to allenenes have been studied in the presence of catalytic amounts of [Hg(OTf)2] in acetonitrile. The catalytic system is quite effective for terminal 1,6-allenynes: allenenes were
