42020-21-3

Basic information

• Product Name: 2,5-DIMETHOXYBENZAMIDE
• Synonyms: 2,5-DIMETHOXYBENZAMIDE
• CAS NO: 42020-21-3
• Molecular Formula: C₉H₁₁NO₃
• Molecular Weight: 181.19
• Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 42020-21-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 295.9 °C at 760 mmHg
• Flash Point: 142.5 °C
• Appearance: /
• Density: 1.16 g/cm³
• Vapor Pressure: 0.00148mmHg at 25°C
• Refractive Index: 1.534
• CAS DataBase Reference: 2,5-DIMETHOXYBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIMETHOXYBENZAMIDE(42020-21-3)
• EPA Substance Registry System: 2,5-DIMETHOXYBENZAMIDE(42020-21-3)

Safety Data

• Hazardous Substances Data: 42020-21-3(Hazardous Substances Data)

Usage

General Description

2,5-DIMETHOXYBENZAMIDE is a chemical compound with the molecular formula C9H11NO3. It is a derivative of benzoic acid and contains two methoxy groups attached to the benzene ring. 2,5-DIMETHOXYBENZAMIDE is commonly used in organic synthesis and has been studied for its potential pharmaceutical properties. It is also used as a building block in the production of various pharmaceuticals and agrochemicals. Additionally, 2,5-DIMETHOXYBENZAMIDE has potential applications in the development of new materials and as a reagent in chemical research. Overall, this chemical compound has diverse uses and applications across various industries.

InChI:InChI=1/C9H11NO3/c1-12-6-3-4-8(13-2)7(5-6)9(10)11/h3-5H,1-2H3,(H2,10,11)

Upstream product

• 490-79-9 2,5-dihydroxybenzoic acid. 
• 150-78-7 1,4-dimethoxybezene 
• 1204-21-3 2-bromo-2',5'-dimethoxyacetophenone 
• 14568-68-4 1,4-dimethoxy-2-vinylbenzene 
• 2612-02-4 5-methoxysalicylic acid 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 75-52-5 nitromethane 
• 2785-98-0 2,5-dimethoxybenzoic acid 
• 2150-40-5 methyl 2,5-dimethoxybenzoate 
• 463-72-9 carbamic chloride 
• 17918-14-8 2,5-dimethoxybenzoyl chloride 

Relevant articles and documents

Hydrosilylative reduction of primary amides to primary amines catalyzed by a terminal [Ni-OH] complex

A terminal [Ni-OH] complex1, supported by triflamide-functionalized NHC ligands, catalyzes the hydrosilylative reduction of a range of primary amides into primary amines in good to excellent yields under base-free conditions with key functional group tolerance. Catalyst1is also effective for the reduction of a variety of tertiary and secondary amides. In contrast to literature reports, the reactivity of1towards amide reduction follows an inverse trend,i.e., 1° amide > 3° amide > 2° amide. The reaction does not follow a usual dehydration pathway.

Tandem synthesis of aromatic amides from styrenes in water

An expedient one-pot synthesis of aromatic amides has been reported from styrenes in the presence of N-bromosuccinimide and iodine by using aqueous ammonia in water. The reaction proceeds through the formation of α-bromoketone as an intermediate in the pr

Aminofluorene-Mediated Biomimetic Domino Amination-Oxygenation of Aldehydes to Amides

A conceptually novel biomimetic strategy based on a domino amination-oxygenation reaction was developed for direct amidation of aldehydes under metal-free conditions employing molecular oxygen as the oxidant. 9-Aminofluorene derivatives acted as pyridoxamine-5′-phosphate equivalents for efficient, chemoselective, and operationally simple amine-transfer oxygenation reaction. Unprecedented RNH transfer involving secondary amine to produce secondary amides was achieved. In the presence of 18O2, 18O-amide was formed with excellent (95%) isotopic purity.