42042-64-8Relevant articles and documents
A mild and facile synthesis of cyclic imides using pyridinium chlorochromate
Yang, Yanyan,Wang, Ge,Cao, Xiaohui,Yan, Xilong,Chen, Ligong
, p. 657 - 658,2 (2020/07/30)
A mild and facile synthetic method of cyclic imides is presented. These compounds are widely used in the synthesis of novel medical, polymeric, photonic and electronic materials. Compared with traditional syntheses, the method reported has several advantages including mild conditions, simplified work-up and low cost.
Synthesis and biological activity of fluoro-substituted pyrrolo[2,3-d]pyrimidines: The development of potential positron emission tomography imaging agents for the corticotropin-releasing hormone type 1 receptor
Hsin, Ling-Wei,Webster, Elizabeth L.,Chrousos, George P.,Gold, Philip W.,Eckelman, William C.,Contoreggi, Carlo,Rice, Kenner C.
, p. 707 - 710 (2007/10/03)
A series of fluoro-substituted 4-(diakylamino)pyrrolo[2,3-d]pyrimidines was synthesized and their binding affinity for corticotropin-releasing hormone type 1 receptor (CRHR1) was investigated. Compounds 11a and 11b possessed very high CRHR1 affinity (K(i) = 3.5, 0.91 nM, respectively). They are promising candidates for the development of 18F-containing nonpeptide PET radioligands for CRHR1. Published by Elsevier Science Ltd.
