42051-04-7Relevant articles and documents
A dicationic, podand-like, ionic liquid water system accelerated copper-catalyzed azide-alkyne click reaction
Javaherian, Mohammad,Kazemi, Foad,Ghaemi, Masoumeh
, p. 1643 - 1647 (2015/01/09)
In this work, an effective, task specific, dicationic, podand-like ionic liquid was synthesized and applied to improve the capability features of click reaction. Moreover, to broaden the scope and decreasing the serious limitations of preparation methods of organic azides, a simple green procedure for the preparation of alkyl azides, the fundamental starting materials in click reactions, from alcohols under solvent-free conditions and microwave irradiation has been reported, for the first time.
A one-pot method for the efficient conversion of aryl- and acyl-substituted methyl alcohols into chlorides
Lai, Gaifa,Tan, Ping-Zhong,Ghoshal, Pallab
, p. 1727 - 1732 (2007/10/03)
A one-pot and efficient conversion of aryl- and acyl-substituted methyl alcohols into the corresponding chlorides is described, which involved tosylation with tosyl chloride and triethylamine in the presence of a catalytic amount of 4-(dimethylamino)pyridine (DMAP) in CH2Cl2, followed by methanol-facilitated replacement of the tosylates with chloride. This mild method is readily amenable to large-scale synthesis.
