420801-23-6Relevant academic research and scientific papers
Conjugate addition reactions of some methylidene 1-benzylpyrimidinetrione derivatives
Abdelghani, Essam
, p. 2413 - 2421 (2007/10/03)
1-Benzyl-2,4,6-pyrimidinetrione (1) reacts at C-5 with aldehydes and the isolated products can easily undergo base-induced transformations by Michael addition. On the contrary,the action of POC13 or piperidine/AcOH on the title trione afforded pyrimido[4′,5prime;:4,5]furo[2,3-d]pyrimidine (16) and a dimer (17), respectively, which in turn, undergo cyclocondensation in Ac2O.
