420803-57-2Relevant academic research and scientific papers
Regio- and stereoselective ring-opening of chiral 1,3-oxazolidin-2-one derivatives by organocopper reagents provides novel access to di-, tri- and tetra-substituted alkene dipeptide isosteres
Oishi, Shinya,Niida, Ayumu,Kamano, Takae,Miwa, Yoshihisa,Taga, Tooru,Odagaki, Yoshihiko,Hamanaka, Nobuyuki,Yamamoto, Mikio,Ajito, Keiichi,Tamamura, Hirokazu,Otaka, Akira,Fujii, Nobutaka
, p. 1786 - 1793 (2007/10/03)
Organocopper-mediated alkylation of β-(N-Boc-2-oxo-1,3-oxazolidin-5-yl)-α,β-enoates has been intensively investigated. Alkylation proceeded regio- and stereoselectively by anti-SN2′ ring-opening to provide a new route to the synthesis of Ψ[(E)-
Diastereoselective Synthesis of ψ[(E)-CMe=CH]- and ψ[(E)-CMe=CMe]-Type Dipeptide Isosteres Based on Organocopper-mediated anti-SN2′ Reaction
Oishi, Shinya,Niida, Ayumu,Kamano, Takae,Odagaki, Yoshihiko,Tamamura, Hirokazu,Otaka, Akira,Hamanaka, Nobuyuki,Fujii, Nobutaka
, p. 1055 - 1057 (2007/10/03)
matrix presented A straightforward synthetic route for the synthesis of diastereomerically pure ψ[(E)-CMe=CH]- and ψ[(E)-CMe=CMe]-type dipeptide isosteres was developed on the basis of regio- and stereoselective anti-SN2′ alkylation of 3-(N-Boc
