420844-43-5

Upstream product

• 563-41-7 semicarbazide hydrochloride 
• 68-12-2 N,N-dimethyl-formamide 
• 54779-81-6 4-methylacetophenone phenylhydrazone 
• 36640-52-5 1-phenyl-3-(p-tolyl)-1H-pyrazole-4-carbaldehyde 

Relevant academic research and scientific papers

Novel bioactive thio- and semicarbazide ligands and their organosilicon (IV) complexes

Ligational behavior of thiosemicarbazones and semicarbazones derived from 1-phenyl-3-arylpyrazole-4-carboxaldehydes towards triphenylchlorosilane has been investigated by elemental analysis, molar conductivity measurements, and IR, 1H, 13C, and 29Si NMR spectroscopic studies. The ligands and their organosilicon complexes have also been evaluated for in vitro antimicrobial activity against some pathogenic bacteria and fungi. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file. Copyright

One-pot synthesis of some new semicarbazone, thiosemicarbazone, and hydrazone derivatives of 1-phenyl-3-arylpyrazole-4-carboxaldehyde from acetophenone phenylhydrazones using Vilsmeier-Haack reagent

Semicarbazone derivatives 3 of 1,3-diphenylpyrazole-4-carboxaldehyde have been synthesized in high yields through a one-pot procedure involving acetophenone phenylhydrazones 1 subjected to Vilsmeier double formylation and workup under new conditions (i.e., treatment with semicarbazide followed by sodium bicarbonate). This method is even suitable for preparing other derivatives (i.e., thiosemicarbazones 4 and hydrazones 5) in high yields. Copyright Taylor & Francis Group, LLC.