42097-33-6Relevant academic research and scientific papers
Synthesis, NMR (1H, 13C and 31P), mass spectral studies and biological activity of 2-aryloxy/alkyl-6-methyl-1,3,2-dioxaphosphorino[5,4-b]pyridine-2-oxides
Devendranath Reddy,Reddy,Naga Raju
, p. 426 - 432 (2007/10/03)
Synthesis of 2-aryloxy/alkyl/phenyl-6-methyl-4H-1,3,2-dioxaphosphorino[5,4-b]- pyridine-2-oxides has been accomplished by condensation of equimolar quantities of various substituted phenylphosphorodichloridates and alkylphosphonic dichlorides with 3-hydroxy-6-methyl-2-pyridine-methanol (lutidine diol) in the presence of triethylamine in dry benzenepyridine. Their structures have been established by elemental analysis, IR, NMR (1H, 13C and 31P) and mass spectral data. A few compounds have been screened for their expected antibacterial and antifungal activities. All the compounds exhibit molecular ions with high abundance and (M-OAr)+ ions are the base peaks in their mass spectra. Long range C-P coupling constant values are evaluated.
